NIH rethinks psychiatry trials
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متن کامل[Randomized controlled trials in psychiatry].
In the past twenty years, evidence based medicine (EBM) has become a dominant paradigm of the contemporary medical practice. Since the emergence of the significant article by Geddes and Harrison in 1997, this doctrine has become part of psychiatry too. According to the rules of EBM, the most valuable clinical data comes from randomized-controlled trials (RCT). Nevertheless there are numerous re...
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The randomized controlled clinical trial is still a relatively new technology for assessing therapeutic interventions, yet innovations in the design and analysis of clinical trials in psychiatry have lagged behind other areas of the biomedical sciences. This delay in the advancement of the science and practice of psychiatric clinical trials is due in part to the inability, dating back to the 19...
متن کاملAlternatives to placebo-controlled trials in psychiatry
Patients receiving placebo do not merely receive an inert substance but also receive support, concern, and reassurance that assists the therapeutic alliance and encourages the positive attitude that forms the basis of cognitive treatment. Response to non-specific factors is seen in all fields of medicine but is particularly potent in psychiatry. The placebo response is variable across settings ...
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ژورنال
عنوان ژورنال: Nature
سال: 2014
ISSN: 0028-0836,1476-4687
DOI: 10.1038/507288a